Anti Glomerular Basement Membrane Disease
Overview This describes a small vessel vasculitis with antibodies against the glomerular and/or alveolar basement membranes in capillaries. Glomerular Basement Membranes (GBM) and Alveolar Basement Membranes contain type 4 collagen with α 3,4,5 chains In this syndrome autoantibodies are formed against the non collagenous domain of the α3 chain of type IV collagen