NSAIDS are known to be nephrotoxic. 1-5% of NSAID users have an adverse kidney event Patients with kidney disease are often advised to refrain from NSAIDS. The thing is NSAIDS work. I’m a nephrologist who takes NSAIDS while advising my patients with CKD to avoid them. What gives? I recently was asked what
Hypotonic Hyponatremia In most cases of hyponatremia there is an excess of H20 relative to Na in the body. This decreases the tonicity (osmolality) of the serum. Water then moves from the extracellular to intracellular space down this osmotic gradient. This causes cellular swelling. Cellular swelling in the brain explains the adverse CNS
Lupus can affect the kidney in many ways. The pathologic classification of lupus nephritis is based on kidney biopsy. Lupus can also affect the kidney in other ways outside of the classification system. This article will provide an overview of pathologic and clinical findings associated with the different types of lupus nephritis. General
This article will provide an overview of diuretics including: Mechanism of action Clinical uses Adverse effects The majority of sodium that is filtered by the glomerulus is reabsorbed in the tubules. If you have normal kidney function and normal diet, less than 1% of the filtered sodium is excreted in the urine. Diuretics
